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pentobarbital will lessen the level or result of elbasvir/grazoprevir by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated. The therapeutic effect of elbasvir/grazoprevir could be minimized if coadministered with solid CYP3A inducers and is also consequently contraindicated.pentobarbital decreases levels of vandetanib by infl